ODCs

Click node...

1 OMIM reference -
4 associated genes
8 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 1

1 OMIM reference -
1 associated gene
4 signs/symptoms

Epidermolytic palmoplantar keratoderma

Epidermolysis bullosa simplex with circinate migratory erythema


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	KRT1	(0.52)	KRT5

Citations in the biomedical literature:

Epidermolytic palmoplantar keratoderma		Epidermolysis bullosa simplex with circinate migratory erythema
	Synonym(s): - Diffuse erythrodermic palmoplantar keratoderma, Voerner type - Diffuse erythrodermic palmoplantar keratoderma, VÃ¶rner type - EPPK - Epidermolytic palmoplantar keratoderma of Voerner - Epidermolytic palmoplantar keratoderma of VÃ¶rner		Synonym(s): - EBS-migr

	Classification (Orphanet): - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare genetic disease - Rare skin disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references


COMMON SIGNS	- Erythema / erythematous lesions / erythroderma / polymorphous erythema

Epidermolytic palmoplantar keratoderma		Epidermolysis bullosa simplex with circinate migratory erythema
	Very frequent - Autosomal dominant inheritance - Hyperkeratosis / ainhum / hyperkeratotic skin fissures - Palmoplantar hyperkeratosis / keratoderma - Warts / papillomas Frequent - Abnormal fingernails - Eczema - Hyperhidrosis / increased sweating		Very frequent - Abnormal pigmentary skin changes / skin pigmentation anomalies - Cutaneous rash - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment